Topiramate and Cognitive Function in Migraine

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Topiramate for migraine prophylaxis.

Topiramate is a neurmodulatory compound with neuron stabilizing properties and is approved for the preventive treatment of migraine in several countries [5]. Several small and large trials have reported good efficacy and safety of topiramate in migraine prophylaxis in adults [6]. The present study was done to study the role of topiramate in migraine prophylaxis in children who either failed to ...

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OBJECTIVE To explore the impact of topiramate on tests of intellect and other cognitive processes. METHODS This was a retrospective study. The neuropsychological test scores of 18 patients obtained before and after the introduction of treatment with topiramate (median dose 300 mg) were compared with changes in test performance of 18 patients who had undergone repeat neuropsychological assessm...

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Prophylaxis of Childhood Migraine: Topiramate Versus Propranolol

OBJECTIVE Headache is a common disabling neurological disorder and migraine comprises more than half the causes of recurrent headaches in children. Despite extended prevalence of this type of headache there is lack of evidence about best drug treatment for migraine. So we aimed to compare the therapeutic effects of these drugs on childhood migraine. MATERIALS & METHODS In the current study, a...

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Topiramate for migraine prevention: an update.

Although the drug topiramate initially was developed for the treatment of epilepsy and received its first US Food and Drug Administration (FDA) approval for that purpose, it subsequently was shown to be effective for the prevention of migraine headaches and is FDA approved for that indication as well. Migraine and epilepsy share a considerable number of biologic and clinical features, and it fo...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 2010

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-24-3-8